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Bath Pain Forum @ Bristol. Dr Frank Porreca
Tue 2 May 2017, 13:00 – 14:00 BST
"Going in circles with opoids for the treatment of pain"
Professor Frank Porreca, University of Arizona
Bath Pain Forum returns to Bristol again to welcome another prestigious expert in the world of pain.
Who is Frank Porreca?
Dr. Frank Porreca is Professor of Pharmacology and Anesthesiology at the University of Arizona in Tucson, Arizona. He also holds an appointment as a Senior Consultant in the Department of Collaborative Research at Mayo Clinic, Scottsdale, Arizona. He trained in Biomedical Engineering at Drexel University and in Pharmacology at Temple University in Philadelphia. His dissertation work focused on drug-receptor theory and understanding of the actions of buprenorphine. He is the author of approximately 500 original, peer-reviewed articles addressing mechanisms of opioids and pain and has been recognized as a “Highly Cited” investigator by PubMed and one of the 10 most cited pharmacologists in the world by the American Society of Pharmacology and Experimental Therapeutics. Dr. Porreca has been honored by the International Association for the Study of Pain with the Ronald Melzack Award and by the American Pain Society with the Frederick W. Kerr Award for Basic Research in Pain.
What will be presented?
The lecture will focus on brain circuits that mediate the relief of pain. New ways of assessing pain in preclinical settings reveal unexpected opportunities for the development of new therapies.
Dr. Porreca’s current research interest remains in the field of pain with particular interest in understanding pain-induced motivational behaviour and reward circuits as a basis for discovery of new therapies with high likelihood of translation. Several themes have have been emphasized including (a) the role of descending modulatory circuits in chronic pain states; (b) the mechanisms by which opioids and stress engage these circuits and (c) the discovery of molecules that can modulate these circuits through novel mechanisms.