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CeASR Seminar- The components of semantic cognition: Evidence from neuropsy...
Wed 29 March 2017, 17:00 – 18:00 BST
The components of semantic cognition: Evidence from neuropsychology, neuroimaging and brain stimulation.
CeASR Seminar- Speech, Language and Health Programme
Guest Speaker: Professor Beth Jeffries, University of York
Organiser- Dr Sarah James
Our neuropsychological research has contrasted degradation of amodal knowledge following atrophy of the anterior temporal lobes (ATL) in semantic dementia (SD), with poor control of semantic retrieval following frontoparietal stroke in semantic aphasia (SA). I will describe the nature of the deficits in these two groups of patients and show that while they have difficulty with the same semantic tasks, they fail them for different reasons. This has led to the hypothesis that patients with multimodal semantic deficits following frontoparietal stroke have difficulty flexibly retrieving knowledge that they still retain. I will present supporting evidence for this view from both fMRI studies of patients and healthy controls, and transcranial magnetic stimulation investigations with healthy volunteers (TMS can briefly disrupt processing in a specific part of the brain and therefore simulate deficits seen in patient populations). This work shows that a distributed network encompassing left prefrontal cortex and regions in temporoparietal cortex is important for flexible semantic retrieval. I will also talk about some preliminary evidence from a semantic training study that we are undertaking in people with semantic aphasia following stroke, aimed at increasing their flexibility in retrieval.
Refreshments provided prior to the seminar