CRUK City of London Centre 2020 Symposium on Cancer Biotherapeutics
Event Information
About this Event
Researchers from the CRUK City of London Centre partners (UCL, King’s Health Partners, Barts/QMUL and the Crick) are invited to the CRUK City of London Centre 2020 Symposium on Cancer Biotherapeutics.
Programme
08:30-09:00 - Registration
09:00-09:10 - Welcome - Professor Tariq Enver
09:10-10:40 - Session 1 - Cancer evolution and tumour heterogeneity
Chair: Professor Francesca Ciccarelli
09:10-09:30 - Targeting Wnt signalling in colorectal cancer - Dr Vivian Li
09:30-09:50 - Post-translationally spliced epitopes of cancer cells - Dr Michele Mishto
09:50-10:10 - Probing the evolution heterogeneity in follicular lymphoma - Dr Giuseppe Palladino
10:10-10:40 - CoL Centre Student talks
Elucidating functional and non-functional genomic heterogeneity in lung cancer - James Black
Understanding exosome-mediated fibrosis to develop new therapies for PDAC - Sarah Duncan
Deciphering new molecular mechanisms driving poor risk Acute Myeloid Leukaemia - Jiexin Zheng
The role of MSCs derived inflammation in the pathogenesis of Myeloproliferative Neoplasms (MPN) and leukaemic transformation - Alessandra Ferrellli
Clonal evolution and immune evasion in primary colorectal cancer (CRC) and metastases - Vinaya Srirangam Nadhamuni
10:40-11:00 - Tea break
11:00-12:20 - Session 2 - Cross-disciplinary approaches enhancing biotherapeutics
Chair: Professor Kairbaan Hodivala-Dilke
11:00-11:20 - Molecular imaging in cancer – new radiotracers for treatment decision-making - Professor Philip Blower
11:20-11:40 - Mechanisms of tumour heterogeneity - Dr Axel Behrens
11:40-11:50 - CoL Centre Development fund
Connecting Single-Cell Ligands, Receptors, and Signals in Tumour Microenvironment Organoids - Dr Chris Tape
11:50-12:00 - CoL Centre Student talks
No more shots in the dark: tracking and quantifying CAR T-cells in solid tumours - Eva Bugallo Blanco
Investigating ADI-PEG20 metabolic therapy to target improved anti-cancer immune responses from CART - Michael Austin
12:00-12:20 - Combining Imaging and Mathematical Modelling to Reconstruct Virtual Tumours - Professor Rebecca Shipley
12:20-12:40 - Radnet
Cancer Research UK RadNet City of London Radiation Research Unit - Professor Gary Royle and Dr Erik Sahai
12:40-13:40 - Lunch
13:40-15:00 - Session 3 - Developing Biological Therapies
Chair: Dr Erik Sahai
13:40-14:00 - Title TBC - Professor Sergio Quezada
14:00-14:20 - Heme oxygenase-1 expressing macrophages in cancer: the wrong place at the wrong time - Dr James Arnold
14:20-14:40 - Targeting L-arginine as a novel cancer therapy - Professor Peter Szlosarek
14:40-14:50 - CoL Centre Development fund
Deep Learning of High Dimensional Genetic, Immune and Clinical Parameters to Predict Patient Response to Immune Checkpoint Blockade - Professor Francesca Ciccarelli
14:50-15:00 - CoL Centre Student talks
Investigation of strategies to avoid off-target toxicity while enhancing CAR T cell function in solid cancers - Charles Agbuduwe
15:00-15:30 - Tea break
15:30-16:40 - Session 4 - Paediatrics Cross-cutting Theme
Chairs: Professors Pamela Kearns and Josef Vormoor
15:30-15:50 - Epigenetic deregulation in malignant brain tumours - Professor Silvia Marino
15:50-16:10 - Senescence in Cancer: Protumourigenic Activities and Novel Therapies - Professor JP Martinez-Barbera
16:10-16:30 - Title TBC - Dr Sara Ghorashian
16:30-16:40 - CoL Centre Student talks
Understanding the role of senescence in paediatric high-grade glioma - Ashley Vardon
16:40-17:00 Closing remarks - Professor Anton Berns
17:00-19:00 Drinks Reception