Dr Sarah Bauermeister, Dementia Platform UK Research Seminar

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Room MU301, Ulster University Magee Campus

Northland Road

Londonderry

BT48 7JL

United Kingdom

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You are invited to attend the UU ISRC/SCEIS Research Seminar to be given by Dr Sarah Bauermeister, University of Oxford that will consist of two talks: “Dementias Platform UK: Accelerating Research Through Cohort Data” (1.30 – 2.30pm) and “Enabling Big Data Analytics For All – Dementias Platform UK Structural Design and Security Architecture” (2.45 – 3.30pm).


Dementias Platform UK (DPUK): Accelerating Research Through Cohort Data (1.30 – 2.30pm)

Dementias Platform UK (DPUK) is a public-private partnership funded by the Medical Research Council to accelerate research and new treatments for dementia. By bringing together records from over 45+ different cohort studies (3 million+ participants) – including brain scans, genetics and clinical records – DPUK is creating the world’s richest source of people data for use in research and drug development for dementia. This free-to-access resource of cohort data is available for use by any researcher who is interested in investigating dementia, whether based within a university or industry context. All data can be accessed after submitting a full proposal by industry or academic researchers. Cohort research teams retain ownership of the data and all access requests require approval from data owners. What data modalities are available and to what level of detail? How can I get access to it? How to write a good DPUK proposal? Answers to these questions and more will be covered.

Enabling Big Data Analytics For All – Dementias Platform UK Data Portal Architecture (2.45 – 3.30pm)

The DPUK Data Portal is a secure and robust data storage and analysis environment that provides a full data upload, curation, and assessment service. The Portal operates a “bring researchers to the data” model as a solution to the challenge of accessing increasingly large, complex, and sensitive datasets. DPUK coordinates access requests enabling data from multiple cohorts to be made with a single request. The Portal can be accessed remotely from any location with desktop commuting facilities and web connectivity. Through a 2-step authentication process, data are accessed on a virtual desktop machine. Transfer of large datasets is decreasingly feasible and on the Data Portal, multiple large-scale datasets can be accessed within a single folder structure. Three virtual desktop machines are available allowing for multi-modal analyses, machine learning and complex analyses to be undertaken. All analyses are conducted from within the Data Portal and datasets cannot be downloaded. DPUK is enabling Big Data analytics to become an easier option in research. This changes the landscape of not only dementia research but the future of how researchers access big datasets. Topics including a DPUK structural design, security architecture, and processing power will be covered.

Proposed Agenda:

1.00 – 1.15 pm – Tea & coffee

1.15 – 2.15 pm – Dementias Platform UK: Accelerating Research Through Cohort Data

2.15 – 2.30 pm – Tea & coffee

2.30 – 3.30 pm – Enabling Big Data Analytics For All – Dementias Platform UK Structural Design and Security Architecture

Bio

Dr Sarah Bauermeister is a Senior Researcher at the University of Oxford and Senior Data Manager for Dementias Platform UK (DPUK), in the research group of DPUK Director and PI, Professor John Gallacher. In DPUK, she is Programme Lead for the DPUK Datathon Intiative; Programme Manager for the user group DPUK Reach; project lead for DPUK Data Curation; and scientific lead for two international DPUK collaborative Alzheimer’s disease (AD) projects. As a Senior Researcher, Dr Bauermeister is a psychometric analyst and her research interests include applying Item Response Theory (IRT) models to mental health, lifestyle, biomedical and healthcare scales, investigating item-level information and scale reliability. She also utilises structural equation modelling (SEM) to explore comorbidities such as cognition and mental health, child adversity and, adult biomedical outcomes and dementia.

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Room MU301, Ulster University Magee Campus

Northland Road

Londonderry

BT48 7JL

United Kingdom

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