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Epigenetics In Practice: Detoxification
Fri 16 June 2017, 09:30 – 16:00 BST
The seminar is designed for healthcare professionals to learn more about the genes, variants and nutrient interactions that impact detoxification and to gain the confidence to use this knowledge in clinical practice.
1. Introduction - Genetics, Epigenetics and Personalised Health
Foundational principals of nutrigenomics in a functional medicine context. Chromosomes, genes and variants. Genetic susceptibilities and resiliance. How nutrients impact gene expression and how genes impact nutrient metabolism.
2. Detoxification - Overview of the Phase 1 and Phase 2 liver pathways their effect on immunity and allergy, nervous system, metabolism and energy, cardiovascular health and hormonal health.
3. Nutrigenomics of detoxification - genes, variants and nutrient interactions - The function of the genes and enzymes involved in Phase 1 - cytochrome P450 (CYP) family and Phase 2 reactions (sulphation, glucuronidation, glutathione conjucation, acetylation, amino acid conjucation and methylation) and the potential impact of genetic variants. The role of nutrients and cofactors such as vitamins B3, B6, B9 (folate), B12, A, flavonoids, phospholipids, glycine, taurine, NAC, cysteine, methionine in detoxification, as well as other anti-oxidant nutrients. The impact of the environment (epigenetics) on toxicity and detoxification - with a focus on endotoxins and exotoxins.
4. Nutrigenomics of oestrogen metabolism and detoxification - A focus on the variants and nutrients that improve and impede oestrogen synthesis, metabolism and elimination
5. Genotype testing and analysis in practice - *case studies - Hands on session to equip practitioners to use nutrigenomics in practice. Linking genetic variants to relevant functional tests and personalised naturopathic nutrition plans.
6. Nutrigenomics resources and support - What next? Websites, specialist groups and meetups, tools and analysis, how to keep up with the latest research.
Accreditation - 5.5 hours CPD (BANT, NNA)
Presenter - Karen Harrison BSc Hons, mBANT, rCNHC