Henry Moss - Experimental Design in the Age of Generative AI

Join us at 12pm for Henry Moss's talk, followed by a light lunch at 1pm. There'll be time for questions at the end of the talk as well as open discussion and networking. Hosted by Neill Campbell.

Title: Experimental Design in the Age of Generative AI - Henry Moss

Abstract: Generative AI is poised to reshape how scientific experiments are conceived and iterated. Yet despite the ability of popular models like diffusion and flow matching to sample from complicated data distributions, one key bottleneck remains: effective experimental design requires more precise control than “unconditional" sampling. The central challenge is finding outputs that are both likely under the generative model but also meet experiment-specific constraints.

We present a framework for extracting low-dimensional, Euclidean latent spaces from any generative model without additional training of the model. The spaces enable standard experimental design and constrained optimisation methods to directly traverse the model’s output manifold. Our approach is architecture-agnostic, computationally lightweight, and generalises across modalities — from images and audio to video and structured objects like proteins.

The venue is UCL's Centre for Artificial Intelligence on the first floor of 90 High Holborn. Unfortunately It is not accessible for wheelchair users. If you are a wheelchair user please get in touch with us.

This event will be in person only.