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Improving the quality of efficacy and mechanisms evaluation (EME) studies:...

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Room 105

25 Gordon Street

UCL

London

WC1H 0AY

United Kingdom

Event description

Description

Efficacy and mechanisms evaluation aims to find out if an intervention works ('efficacy'), and how test the mechanism through which it works ('mechanisms evaluation').

This free one day training course held in UCL in London is aimed at medical statisticians and researchers analysing clinical trial data, and who want to know how to answer these questions.

The course will introduce statistical methods for analysing EME studies, including hands on practical sessions using the Stata and R statistical software packages.

This training day is funded by the MRC North West Hub for Trials Methodology Research (NWHTMR).

The agenda for the day is planned to be:

9:30 – 9:45 Registration
9:45 – 10:00 Introduction and setup
10:00 – 10:45 Session 1: Adjusting for non-compliance using instrumental variables
10:45 – 11:30 Practical 1: Adjusting for non-compliance in a trial of a psychotherapy intervention
11:30 – 11:45 Coffee break
11:45 – 12:30 Session 2: Adjusting for non-compliance using inverse probability weighting (IPW)
12:30 – 1:00 Practical 2: Using IPCW in a cancer trial with treatment switching
1:00 – 1:45 Lunch
1:45 – 2:00 Practical 2: Summary
2:00 – 3:00 Session 3: Mechanisms evaluation using mediation analysis
3:00 – 3:15 Coffee break
3:15 3:45 Practical 3: Mediation analysis in randomised trials
3:15 – 4:15 Session 4: Design implications for trials of efficacy and mechanisms evaluation
4:15 – 4:30 Summary and close of day

If you have any questions please email us using the Contact button below.

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Date and Time

Location

Room 105

25 Gordon Street

UCL

London

WC1H 0AY

United Kingdom

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