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Inaugural Lecture Series: A lifecourse approach to osteoporosis: observatio...

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Lecture Theatre 1, Level B, South Academic Block, University Hospital Southampton

Tremona Road

Southampton

SO16 6YD

United Kingdom

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Title: A lifecourse approach to osteoporosis: observation, mechanism and intervention

Speaker: Professor Nicholas Harvey

Synopsis of Presentation:

Nicholas Harvey is Professor of Rheumatology and Clinical Epidemiology at the University of Southampton, and co-leads an MRC programme focused on the lifecourse epidemiology of bone and joint disease, at the MRC Lifecourse Epidemiology Unit. He originally trained in medicine at the Universities of Oxford and Cambridge Medical Schools, with SHO training in Newcastle upon Tyne and Stoke on Trent. During his rheumatology specialty rotation in Wessex, he undertook his PhD at the then MRC Epidemiology Resource Centre, exploring the early life determinants of bone mass in children born to the Southampton Women’s Survey. Over the last decade his research has evolved to integrate, across the lifecourse, observational epidemiology and laboratory science to inform novel interventions aimed at reducing fracture risk.

A fracture (broken bone), occurring most commonly as a result of a trip or fall, will affect one in two women and one in five men from age 50 years onwards. Such fractures cost the UK economy around £4 billion per year, and are associated with substantial ill-health and reduced lifespan. A major risk factor for these events is low bone mass (osteoporosis). Work at the MRC Lifecourse Epidemiology Unit, University of Southampton, has demonstrated that bone mass is determined by factors acting at various times over the whole of life, even as early as in the womb.

The aim of Professor Harvey’s research is to understand, across the lifecourse, what increases the risk of such osteoporotic fractures, to investigate mechanisms that explain these relationships, and to develop interventions which might improve bone mass and reduce fracture risk across populations. In his lecture, he will describe the work that he has undertaken with colleagues in Southampton and collaborators around the world to address these aims. Professor Harvey will use his research exploring the role of vitamin D supplementation in pregnancy to illustrate the scientific progression from observation to intervention, and translation to potential novel public health approaches, which may ultimately reduce the risk of osteoporotic fractures in future generations.

Refreshments: 16:45

Lecture: 17:15

A wine and canapé reception will follow in the Lecture Theatre foyer until 19:00.

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Lecture Theatre 1, Level B, South Academic Block, University Hospital Southampton

Tremona Road

Southampton

SO16 6YD

United Kingdom

View Map

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