MAC 2025: Advances in Mitochondrial Mechanisms and Therapy

Summary

This meeting will revolve around three main topics: i) Mitochondrial Biology; ii) Mitochondrial role in Pathology and iii) Mitochondrial Pharmacology and Therapeutic advances. It is an occasion for scientific exchange which will sit under the overall arching umbrella of the community within the community that has established and supported the series of MAC meetings whose acronym refers to Mitochondria, Ageing and Cancer. The format will see invited talks complemented by selected ones from the abstracts. Poster sessions will also run together with occasions for interactions with the leaders in the field who have agreed to contribute to the event. It has set the most immediate outcomes in: Raising interest in the topic; informing attendees of the frontiers in mitochondrial research; Consolidating a national and international mitochondrial community, and finally Delineating key aspects of interest on which to establish collaborative networks for major grant applications.

Mitochondria are essential to cellular health, and a growing number of diseases have been linked to mitochondrial dysfunction, making these organelles a critical focus in the pursuit of precision medicine. This meeting aims to highlight the latest advances in mitochondrial research and explore how this rapidly expanding knowledge can be leveraged for medical innovation

Leading national and international experts will come together to present and discuss their findings, fostering inspiration and new insights. The meeting will cover cutting-edge developments in mitochondrial science, diagnostic techniques, and pharmacological strategies related to therapeutic interventions.

Our goal is to create a platform that engages specialists while also being accessible to a wider audience. This initiative is designed to support the scientific community working on biomedical research and translational medicine.

The meeting will offer valuable insights making it especially relevant for graduate students, early-career researchers, and clinical fellows. Additionally, it will provide knowledge of broad relevance to professionals in the biotech and pharmaceutical industries.

Event Schedule

Day 1 - Wednesday 3rd December 2025 - Mitochondrial Biology

12.00 Arrival and Registration

1.00 p.m. Welcome Address

1.15 - 5.30 Various Talks and Presentations (coffee breaks included)

5.30 - 8.00 p.m Welcome Drinks (venue tbc)

Day 2 - Thursday 4th December 2025 - Mitochondria in Ageing-Related Conditions

9.00 a.m - 5 p.m. various talks and presentations (coffee breaks and lunch included)

Day 3 - Friday 5th December 2025 - Pharmacology & Therapeutic Advances

9.00 a.m. - 1.00 p.m. Various Talks and Concluding Remarks

Confirmed Speakers

Prof. Mike Murphy (UK)

Prof. Jared Rutter (USA)

Prof. Tomas Langer (DE)

Prof. Jose Antonio Henriquez (ES)

Prof. Sarah-Maria Fendt (BE)

Prof. Idliko Szabo (IT)

Prof. Valentina Perissi (USA)

Dr. Melanie Pallard (FR)

Dr. Catherine Brenner (FR)

Prof. Stuart Rushworth (UK)

Prof. Jiri Neuzil (AUS, CR)

Prof. Robert Pitchleay (UK)

Prof. Jo Bateman (UK)

Prof. Stpehen Tait (UK)

Prof. Phil Eaton (UK)

Prof. Dunja Aksentijevic (UK)

Dr. Dave Owen (UK)

Prof. Paulo Oliveira (PT)

Prof. Mike Berridge (NZ)

Prof. Shazib Pervaiz (SGP)