Please see the programme below:

MTRC Conference Programme – 4th and 5th September 2024, Hughes Hall, Cambridge

Day 1 – Wednesday 4th September

09:15-09:20 - MTRC Director - Welcome

09:20-09:25 - Prof Graham Ball – Opening

SESSION CHAIR: MTRC DIRECTOR

09:25-10:05 - Keynote: Prof Yonghong Peng, ARU – ‘AI in Medicine and Health: unlocking its potential to transform the future health’

10:05-10:30 - Prof Luis Roseiro, Coimbra Institute of Engineering, Portugal – ‘Functional Prototypes in Applied Biomechanics’

10:30-10:55 - Dr Talip Çelík, Kocaeli University, Turkey – ‘Fatigue examination in biomedical implants and hip prosthesis’

10:55-11:15 COFFEE BREAK

SESSION CHAIR: PROF MOHAMMAD NAJLAH

11:15-11:40 - Ibrahim Mutlu, Kocaeli University, Turkey – ‘Potential of 3D Printed Electroactive Polymer Composite Layers for Hand Therapy and Prosthetic Applications’

11:40-12:05 – Pradeep K Adapala and Dr Sudhakara Reddy Pondugula, DCS Pharma – ‘Repurposed Drugs in Pharmaceutical Sciences: A Paradigm Shift in Product Development, Expanding Horizons and Enhancing Efficiency’

12:05-12:30 - Dr Agilandiswari Arumuga Jothi, Mid and South Essex NHS Foundation Trust – ‘Randomised controlled trial of remotely supervised exercise versus self-directed exercise for intermittent claudication (RESET 2 study)’

12:30-12:55 - Dr Gouri Koduri, Mid and South Essex NHS Foundation Trust – ‘Understanding the connection between Connective tissue disease and the Lungs’

12:55-13:50 LUNCH BREAK

SESSION CHAIR: DR SILVIA CIRSTEA

13:50-14:15 - Dr Havovi Chichger, ARU – ‘Activation of T1R3 anchors ACE2 at the pulmonary endothelial cell surface to attenuate vascular disruption induced by the SARS-CoV-2 spike protein’

14:15-14:40 - Dr Rudolph Schutte, ARU – ‘Alcohol and arterial stiffness in middle-aged and older adults: Cross-sectional evidence from the UK Biobank study’

14:40-15:05 - Prof Abdelbary Elhissi, Qatar University, Qatar – ‘Lipid and surfactant-based systems for pulmonary drug delivery’

15:05-15:30 - Dr Grisha Pirianov, ARU – ‘Preclinical development of the Toll like receptor 4 (TLR4) antagonist FP12 as a lead compound targeting the DAMP/TLR4 axis in lethal influenza infection’

15:30-15:50 COFFEE BREAK

SESSION CHAIR: PROF SELIM CELLEK

15:50-16:15 - Prof Selim Cellek, ARU – ‘Impact of a new combination anti-fibrotic therapy discovered in ARU’

16:15-16:40 - Dr Alice Lapthorn, ARU – ‘Repurposing drugs to find new medicines to promote wound healing’

16:40-17:05 - Kieran Feltham, ARU – ‘Repurposing fully annotated compounds for the prevention of hypertrophic scarring’

17:05-17:30 - Dr Sophie Harding, ARU – ‘Development of a high-throughput phenotypic screening assay to identify novel therapeutics for the prevention of intra-abdominal adhesions’

17:30-17:35 - Prof Barbara Pierscionek / Prof Mohammad Najlah – Close

Exhibitors:

DCS Pharma (Pradeep K Adapala and Dr Sudhakara Reddy Pondugula)

Wonderful Scientific (Dr Andrew Lonergan)

Medilink Midlands (TBC)

Office of Translational Research at Cambridge (Anita Marguerie de Rotrou)

eg technology (Rouzet Agaiby)

MTRC Conference Programme – 4th and 5th September 2024, Hughes Hall, Cambridge

Day 2 – Thursday 5th September

09:15-09:20 - Prof Barbara Pierscionek – Welcome

SESSION CHAIR: PROF BARBARA PIERSCIONEK

09:20-10:00 - Keynote: Prof Bhaskar Dasgupta, Mid and South Essex NHS Foundation Trust – ‘The GCA-PMR spectrum: from diagnosis to management’

10:00-10:25 - Dr Jodie Harrington, ARU (online) – ‘Characterisation of Ocular Lens Model from Human Induced Pluripotent Stem Cells (hiPSCs)’

10:25-10:50 - Dr Patrick Varga-Weisz, University of Essex – ‘Microbiota shaping anatomy’

10:50-11:10 COFFEE BREAK

SESSION CHAIR: DR GRISHA PIRIANOV

11:10-11:35 - Dr Joaquín de Navascués, University of Essex – ‘A Drosophila model of radiotherapy toxicity to normal tissue’

11:35-12:00 - Dr James Birrell, University of Essex – ‘Mechanistic studies of [FeFe] hydrogenates: a tale of two sites’

12:00-12:25 - Prof Mohammad Najlah, ARU – ‘A Novel Approach to Fighting Cancer: Drug Repurposing Combined with Efficient Nanotechnology!’

12:25-12:50 - Dr Ketan Patel, University of Reading – ‘Improved health by combining dietary restriction and promoting muscle growth in DNA repair-deficient progeroid mice’

12:50-13:50 LUNCH BREAK

Parallel workshop with Cambridge Enterprise, Peter Richards Room – 14:00-17:00

SESSION CHAIR: DR DAN ROBBINS

13:50-14:15 - Dr Dan Robbins, ARU - 'Presenting features of Giant Cell Arteritis (GCA)'

14:15-14:40 - Gareth Williams, Marks and Clerk - 'Artificial Intelligence in the MedTech Industries: Intellectual Property Considerations'

14:40-15:05 - Dr Cagatay Tasdemirci, ARU - 'Enhancing Remote Robotic Surgery: Comparative Analysis of Control Systems and Haptic Feedback Techniques'

15:05-15:30 - Dr Ashim Chakraborty, ARU - 'Predictive risk stratification of premature babies using machine learning: A clinical decision support system'

15:30-15:50 - COFFEE BREAK

SESSION CHAIR: DR JASMINE SAMVELYAN

15:50-16:25 - Dr Jasmine Samvelyan, ARU - 'Characterisation of growth plate dynamics in post-traumatic murine models of osteoarthritis'

16:25-16:40 - Kamakshi Jani, ARU - 'Developing non-invasive mechanically loaded models to identify mechanisms underpinning osteoarthritis predisposition'

16:40-16:55 - 'Mr Sunil Kumar, Cambridge University Hospitals - 'Core Outcome Measures in Hip Preservation Surgery'

16:55-17:10 - Mr Anuj Punnoose, Cambridge University Hospitals - 'Rehabilitation in FAI: The Cambridge Pilot'

17:10-17:25 - Mr Arman Memarzadeh, Cambridge University Hospitals - 'Muscle Strength and FAI: What do We Know?'

17:25-17:50 - Mr Vikas Khanduja, ARU, 'Role of Technology in Hip Preservation Surgery'

17:50-17:55 - Prof Barbara Pierscionek and Prof Yonghong Peng, ARU - Closing Remarks

Exhibitors:

DCS Pharma (Pradeep K Adapala and Dr Sudhakara Reddy Pondugula)

Wonderful Scientific (Dr Andrew Lonergan)

Medilink Midlands (TBC)

Office of Translational Research at Cambridge (Anita Marguerie de Rotrou)

eg technology (Rouzet Agaiby)

Posters – Wednesday 4th and Thursday 5th September

Shadi Amor - 'Analysis of Growth Plate Dynamics using Avizo Imaging Software on Mechanically Loaded Osteoarthritis Murine Model'

Nathan Bytheway - 'The effect of exercise on gait biomechanics in people with knee osteoarthritis'

Prof Selim Cellek - 'Development of a phenotypic screening assay to discover neoadjuvant treatments to prevent metastasis'

Kieran Feltham - 'Adaptation of a phenotypic screening assay to incorporate 384-well plates: opening the door to high throughput screening'

Vincenzo De Franco - 'Harvest or not to harvest: a step-wise decision for radial artery graft selection in surgical coronary revascularisation'

Kamakshi Jani - 'Investigating growth plate dynamics using mechanically loaded models to identify mechanisms underpinning osteoarthritis predisposition'

Dr Alice Lapthorn - 'A novel drug combination produces a synergistic effect when inhibiting myofibroblast transformation in an in vitro model of hypertrophic scarring'

Dr Alice Lapthorn - 'Development of a high-throughput phenotypic screening assay to identify novel therapeutics for the prevention of intra-abdominal adhesions'

Dr Ankur Thapar, Gui Movio and Chloe Knight - 'Scoping review of topical negative pressure and integration of Biodegradable Temporising Matrix'

MTRC's Third Annual Research Conference