New tests and treatments for prostate cancer

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Glenister Lecture Theatre, Charing Cross Hospital, Margravine Road, London W6 8RP

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At the next Imperial College Academic Health Science Centre (AHSC) seminar, an expert from Imperial College Healthcare NHS Trust will pair up with an academic from Imperial College London to talk about their latest work to detect and treat prostate cancer.

Identifying prostate cancer

Dr Sylvain Ladame, from the College’s Department of Bioengineering, will talk about his work to develop new screening tests for early diagnosis of prostate cancer.

Current tests for prostate cancer look for raised levels of a protein called prostate specific antigen (PSA) which is produced by normal, as well as malignant, cells of the prostate gland.

This may or may not indicate cancer that requires treatment. Use of the PSA test can however lead to more people having invasive investigations which might include unnecessary surgery.

Dr Ladame and his team are developing a low-cost test to detect early-stage prostate cancer at the point of care. The test works by detecting biomarkers in blood to help diagnose prostate cancer with higher specificity than tests that are currently offered, and can provide results in a few hours.

The researchers hope the test, which will use a small sample of blood, could eventually be available in GP surgeries.

Treating enlarged prostate

Professor Hashim Ahmed, Consultant Urological Surgeon at the Trust, will outline his work on developing pioneering new treatment which could improve the lives of thousands of men with an enlarged prostate.

One in three men over the age of 50 are thought to be affected by an enlarged prostate. Symptoms can include needing to visit the toilet more frequently and with more urgency and experiencing difficulty emptying their bladder.

The new procedure, which is called Rezum Water Vapour, injects small amounts of steam into the prostate. The steaming process permeates throughout the tissue which then allows the gland to shrink as it repairs itself, relieving the symptoms.

The new technique aims to replace a procedure which takes over an hour and includes 2–3 days of hospital stay with a 10–15 minute procedure under sedation/local anaesthetic with patients able to go home that same day.

Professor Ahmed was the first to perform the procedure in London at Charing Cross Hospital.

Lunch will be served after the presentations.

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Glenister Lecture Theatre, Charing Cross Hospital, Margravine Road, London W6 8RP

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