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The Roslin Institute

Easter Bush Campus

Midlothian

EH25 9RG

United Kingdom

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Scope

The Symposium on African Livestock Trypanosomes will be an informal meeting aimed at researchers currently active in or interested in studying the biology of these important pathogens. The symposium will update on recent research findings, as well as creating a forum for discussions around opportunities and challenges for advancing livestock trypanosome research.

Agenda

Thursday 11th January 2018

12:00-13:00 Registration and lunch

13:00-13:10 Welcome, Professor Eleanor Riley, Director, Roslin Institute

13:10-13:30 Introduction, Dr Liam Morrison, Roslin Institute, University of Edinburgh

13:30-14:00 Minor Groove Binders: a novel class of potent trypanocide, Prof Mike Barrett, University of Glasgow

14:00-14:30 Comparative metabolism of T. brucei & T. congolense, Dr Pieter Steketee, Roslin Institute, University of Edinburgh

14:30-15:00 In vivo drug screening models of Trypanosoma congolense and T. vivax, Dr Kevin Read, Drug Discovery Unit, University of Dundee

15:00-15:30 Tea & coffee

15:30-16:00 Using reverse vaccinology to identify vaccine candidates for animal African trypanosomiasis. Dr Delphine Autheman, Sanger Institute

16:00-16:30 Rapid evolution of cell surface receptors between African trypanosome species. Prof Mark Carrington, University of Cambridge

16:30-17:00 Interspecific interactions and density dependent adaptations in Trypanosoma congolense. Dr Eleanor Silvester, University of Edinburgh

17:00-18:00 Discussion: Community priorities for the livestock trypanosomes.

18:00 Drinks reception

19:30 Dinner

Friday 12th January 2018

9:00-9:30 Epidemiology of livestock trypanosomes. Dr Harriet Auty, Scotland’s Rural College (SRUC)

9:30-10:00 How variable is variable? Global antigenic diversity in natural trypanosome populations. Dr Andrew Jackson, University of Liverpool

10:00-10:30 Challenging trypanosome antigenic variation paradigms using natural systems. Dr Christina Cobbold & Dr Richard McCulloch, University of Glasgow

10:30-11:00 T. congolense antigenic variation is driven by RNA polymerase I from a brucei-like expression site body. Dr Bill Wickstead, University of Nottingham

11:00-11:30 Tea & coffee

11:30-12:00 Trypanosoma evansi and Trypanosoma equiperdum - livestock trypanosomes 'Out of Africa'. Dr Achim Schnaufer, University of Edinburgh

12:00-12:30 Mechanisms of pathogenesis in African trypanosomiasis: a key role for aberrant NK cell mediated cytotoxicity. Prof Sam Black, University of Massachusetts

12:30-13:15 Wrap up discussion: Opportunities for collaborative networks in the livestock trypanosomes.

Lunch and departure

Further information

For information about how to get to The Roslin Institute please visit our website. Tours of the Roslin Institute and its facilities will be available at the end of the symposium upon request.

Transport and accommodation advice can be provided to participants.

All attendees from outside the UK are responsible for making sure they have the correct documentation to enter the country. Unfortunately we are not able to provide you with an invitation letter. Please refer the UK Border Agency (UKBA)’s guide.

Twitter: #SALTed2018


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Date and Time

Location

The Roslin Institute

Easter Bush Campus

Midlothian

EH25 9RG

United Kingdom

View Map

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