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The Centre for Biostatistics Spring Seminar - Individual Patient Data Meta-...

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MANDEC

Manchester

M15 6FH

United Kingdom

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This year’s Centre for Biostatistics Spring Seminar will include three speakers focusing on the topic Individual Patient Data (IPD) Meta-Analysis. The seminar will aim to be accessible to all with the first speaker asked to provide a brief introduction to the topic.

We are excited to confirm three excellent speakers – Dr Jayne Tierney (UCL), Prof Richard Riley (Keele) and Dr Sarah Nevitt (Liverpool).

Jayne Tierney has been a Research Scientist at the MRC Clinical Trials Unit at UCL since its formation in 1999 and is one of the co-convenors of the Cochrane IPD Meta-analysis Methods Group. For more than 20 years, she has been responsible for designing and conducting systematic reviews and meta-analyses to rigorously re-evaluate the effectiveness of therapies. Jayne leads a small group that has published international, collaborative, individual participant data reviews in bladder, cervix, lung, oesophagus, and soft-tissue cancer and in addition to cancer, systematic reviews of aggregate data in stroke, HIV, and fertility medicine. Jaynes methodological research looks to improve how systematic reviews and meta-analyses are conducted and analysed. Current interests include how to perform timely and reliable aggregate data meta-analyses, and how best to evaluate treatment covariate interaction in meta-analysis. Jayne is also the Deputy Director of the London Hub for Trials Methodology Research.

Richard Riley is a Professor of Biostatistics at Keele University, whose role focuses on statistical and methodological research for prognosis and meta-analysis. Richard is an expert on statistical methods for meta-analysis (specialising in methods for dealing with multiple correlated outcomes) and prognosis research (co-leading the PROGRESS initiative (PROGnosis RESearch Strategy) seeking to improve the standards of prognosis research). He combines his meta-analysis and prognosis interests through the development and validation of prognostic models using IPD from multiple studies, especially in the cancer field. He has received numerous healthcare related grants, from funders including the MRC and NIHR, and has published over 100 applied and methodological research articles. Richard is also a Statistics Editor for the BMJ and a co-convenor of the Cochrane Prognosis Methods Group.

Sarah Nevitt is a Postdoctoral Researcher at the University of Liverpool, where she has been working since 2011. Sarah is the Statistical Editor of the Cochrane Epilepsy Group and her role also includes working within the Clinical Trials Unit at the University of Liverpool and performing Health Technology Assessment on behalf of the National Institute for Health and Care Excellence. Sarah has authored eight IPD meta analyses and an IPD network meta-analysis of anti-epileptic drug trials and has also been involved in several methodological projects related to IPD analyses and data sharing. Sarah has an active research interest in data sharing and data anonymisation and was awarded a PhD in late 2017, thesis titled “Data sharing and transparency: the impact on evidence synthesis.” Sarah also has external collaborations as a member of Pharmaceutical Users Exchange Data Transparency Working Group and has recently been appointed to EMA Technical Anonymisation Group.

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MANDEC

Manchester

M15 6FH

United Kingdom

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