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Francis Crick Institute

1 Midland Road



United Kingdom

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The objective of this joint meeting is to highlight new research in the Infections & Immunity area from groups working in London and elsewhere in the UK. The meeting aims to encourage free exchange of ideas, cross-disciplinary interactions and new collaborations. Two poster sessions will provide a forum for Postdocs and students to present their work. If you would like to submit a poster, please send your abstract to events@crick.ac.uk and we will be in touch with further details. Drinks and light finger food will accompany the poster session on Monday evening.


Monday 5 November

08:00-09:20 - Registration

09:25 - Steve Ley (Imperial College London): Welcome and Introduction

09:30 - Fiona Powrie (Oxford University): Gut reactions: Immune pathways in the intestine in health and disease

Innate immune response to pathogens

10:10 - Felix Randow (LMB, Cambridge): How cells defend their cytosol against bacteria

10:35 - Max Gutierrez (Francis Crick Institute): Mycobacterium tuberculosis survival within lymphatic endothelial cells

11:00 - Charlotte Odendall (King's College London): Interferon: Tug of war between Host and Pathogen

11:25-11:45 - Refreshment break

11:45 - Teresa Thurston (Imperial College London): Innate immune inhibition by Salmonella effector

12:10 - Marina Botto (Imperial College London): C1q in health and disease - roles outside the complement system

12:35 - Dave Sansom (University College London): Control of self-tolerance by the CTLA-4 immune checkpoint

13:00-14:30 - Lunch and poster session

Autoimmunity & infections

14:30 - Mala Maini (University College London): Harnessing liver-resident T cells for hepatitis B cure

14:55 - Ian Goodfellow (Cambridge University): Identification of host pathways involved in the norovirus life cycle

15:20 - Ken Smith (Cambridge University): New pathways governing prognosis in immune-mediated disease proteins

15:55-16:30 - Refreshment break

16:30 - Claudia Mauri (University College London): Regulatory B cells and gut microbiota: can we ameliorate arthritis

16:55 - Robert Wilkinson (Francis Crick Institute): Immunology of HIV-associated tuberculosis

17:20 - Andy Waters (Glasgow University): The varied beginnings of sexual development in malaria parasites

18:00-20:00 - Drinks and finger food

Tuesday 6 November

Lymphocyte function & immunotherapy

09:00 - Sarah Teichmann (Sanger Institute): Immunogenomics: one cell at a time

09:25 - Ben Seddon (University College London): Regulation of T cell development and survival by TNF signalling

09:50 - Giovanna Lombardi (King's College London): Optimising the use of regulatory T cells to promote transplantation tolerance

10:15 - Edith Hessel (Refractory Respiratory Inflammation DPU. GSK): PI3Kdelta inhibitors: innovative medicines for uncontrolled respiratory diseases

10:40-11:10 - Refreshment break

Life long immunity

11:10 - Tracy Hussell (Manchester University): Mechanisms of immune adaption in the inflammation-adaped lung

11:35 - George Kassiotis (Francis Crick Institute): A million-year long infection

12:00 - Deena Gibbons (King's College London): Neonatal Immunology and the CXCL8-producing T cell

12:25 - Chris Chiu (Imperial College London): Protective immunity in human experimental influenza and RSV infection

12:50-14:30 - Lunch and poster session

Infection & immunity in cancer

14:30 - Julian Downward (Francis Crick Institute): Mechanisms of tumour immune evasion driven by RAS oncogenes

14:55 - John Maher (King's College London): Pan-ErbB CAR-T therapy of Head and Neck Cancer

15:20 - Paul Farrell (Imperial College London): EBV genome sequence variation: geography, function and disease

15:55 - Caetano Reis E Sousa (Francis Crick Institute): Pathways in the initiation of immunity to cancer

16:20 - Steve Ley (Imperial College London): Concluding comments

16:30 - End of meeting

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Francis Crick Institute

1 Midland Road



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