UK CEiRSI In Silico Regulatory Airlock Panel Session: Assessing Computational Simulations for Wear Testing: A Case Study in Total Hip Joint Replacements
Thursday 9th October, 2025 │14:00 – 16:00 BST
This session is a key part of the UK CEiRSI project – where interdisciplinary experts will meet to examine standards and frameworks for the credibility assessment of computational Simulations for wear testing: a case study in total hip joint replacements.
About this Case Study:
Aim: To establish recommendations for the credibility of in-silico hip simulator models in predicting and optimising functional testing, by assessing the risk of device wear considering surgeon, implant, and patient factors, and evaluating whether new bearing technology reduces wear compared to conventional options while identifying optimal patient selection criteria to minimise failure
Agenda:
- Rationale for the use of in-silico models for patient-centred wear-testing of total hip joint replacements
- Panel credibility recommendations for the credibility assessment of in-silico hip simulator models
- Panel and audience Q&A
Case Study Leads:
- Dr Danielle de Villiers, MatOrtho
- Prof Michael Bryant, University of Birmingham
Zoom details: See Online Event Page and Order Confirmation Email for meeting details
About UK CEiRSI: The UK’s first Centre of Excellence in In-Silico Regulatory Science and Innovation (UK CEiRSI) advances computational evidence in healthcare, bringing together academia, industry, and regulators to shape global standards.
About the In Silico Regulatory Airlock Panel Sessions: These sessions bring together individuals from academia, industry, and regulatory bodies, to examine the practical strengths and weaknesses of existing international credibility frameworks. Each Case Study Panel Session will focus on a hypothetical medical intervention (drug or device) that will enable us to interrogate and refine current standards and frameworks for the credibility assessment of model-informed evidence.
