Webinar: Fragment Screening using 19F NMR at the UCL School of Pharmacy
Join Dr Nikita Harvey and Dr Christopher Waudby to delve into the subject and interact with research fellows.
Date and time
Location
Online
Good to know
Highlights
- 1 hour
- Online
About this event
UCL’s Research Capabilities Webinar Series: Fragment Screening using 19F NMR at the UCL School of Pharmacy: Principles, Practice, and Applications
Date: Friday 19 Sep 2025
Time: 1400 - 1500
Venue: Online
Open to: All
Speaker: Dr Nikita Harvey, Specialist Services Manager (NMR), UCL School of Pharmacy; Dr Christopher Waudby, Lecturer in Biomolecular NMR at the School of Pharmacy, UCL School of Pharmacy
Chaired by: Prof. Matthew Todd, Chair of Drug Discovery, UCL School of Pharmacy; Co-chair of the UCL Therapeutic Innovation Networks (TINS) - Small Molecules
About the webinar:
The speakers will introduce a new 19F NMR fragment screening platform at the UCL School of Pharmacy, which provides an efficient approach to drug discovery by screening a small but chemically diverse library of ca. 500 compounds for weak but atom-efficient binders.
The talk will cover the principles of fragment-based drug discovery and NMR spectroscopy, practical aspects of the rapid, multiplexed screening workflow – which requires just 2-3 mg of sample – and the downstream analysis and software used to identify hits. The speakers will examine a number of case studies involving screening against both protein and nucleic acid targets, and additional capabilities of NMR to drug discovery and development will also be discussed, highlighting the broader utility of this technique beyond initial fragment screening.
About the UCL’s Research Capabilities Webinar Series:
This webinar series is organised by the UCL Therapeutic Innovation Networks (TINs) - Small Molecules to highlight UCL’s Research Capabilities that enable effective translational research for patient and public benefit. The series aims to encourage multidisciplinary collaborations within and beyond UCL. Academics from the UCL biomedical community are invited to share subjects of interest from their research expertise and interact with research fellows.
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About Therapeutic Innovation Networks (TINs):UCL Translational Research Office (TRO) established the Therapeutic Innovation Networks (TINs) to create a ‘critical mass’ of academic researchers and industry professionals around six modalities: i) Small Molecules; ii) Cell & Gene Therapies; iii) Biologics; iv) Re-purposing; v) Devices & Diagnostics; vi) Regenerative Medicine. The TINs’ unique approach has been pioneering in providing support for UCL academics around pilot data collection, translational training, funding opportunities and multidisciplinary collaborations across institutions, partner hospitals and the industry.
About Translational Research Office:
UCL Translational Research Office (TRO) is an integral part of UCL’s biomedical research powerhouse. As an expert team of applied scientists and business developers, we support our researchers in realising their translational ambition by offering strategic advice, funding support, and bridging the gap with industry to help establish collaborations that drive the pipeline of therapeutic, device and diagnostic innovations.
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