Forging New Links: Cellular and Developmental Systems

The MAHSC Women and Children Domain collaborates closely with The University of Manchester’sCellular and developmental systemsand Evolution, Systems and Genomics strategic research domains to ensure that scientific discoveries can be channelled towards clinical practice. These collaborations focus on the understanding of gene and genome function and the processes that are fundamental to our understanding of life, such as basic cell and developmental biology processes.Click here to find out more about the MAHSC Women and Children DomainClick here to find out more about the University of Manchester Cellular and Developmental Systems Domain

The MAHSC Women and Children Domain

The <A HREF="https://www.healthinnovationmanchester.com/our-expertise/clinical-research-excellence-2/women-children/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">MAHSC Women and Children Domain</A> and The University of Manchester <A HREF="https://www.bmh.manchester.ac.uk/research/domains/cellular-development-systems/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Cellular and Developmental Systems Domain </A> would like to invite clinicians, clinical scientists, clinical research fellows, nursing, midwifery and allied health professionals to this event to develop new research collaborations in Manchester.   
The event is focused on research in cellular and developmental systems; processes that are fundamental to our understanding of life. The meeting will be particularly of interest to people working in these areas: arthritis, developmental disorders, cancer, chronic diseases, fibrosis, healthy ageing, inflammation and repair, neurodegeneration, rare diseases and identifying targets for disease intervention.
Audience: Clinicians, Clinical Scientists, Clinical Research Fellows, Nursing, midwifery and allied health professionals 
13:00 Lunch/Networking
13:30 Welcome /Purpose of meeting  - <A HREF="https://www.bmh.manchester.ac.uk/about/people/leadership/peter-clayton/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Peter Clayton</A>
13:40 Examples of scientist - clinican collaborations
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<A HREF="https://www.research.manchester.ac.uk/portal/william.newman.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Bill Newman</A> 
Using hiPSCs to understand ‘What inhibits growth in 3-M syndrome?’ <A HREF="https://www.researchgate.net/profile/Steven_Woods2" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Steven Woods</A>
 
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13:50 <A HREF="https://www.bmh.manchester.ac.uk/research/domains/cellular-development-systems/cell-dynamics/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Cell Dynamics</A>
Research covers the role and regulation of cytoskeleton and membranes from the single cell level to whole organisms. Their regulatory mechanisms are closely linked to many common diseases, including developmental disorders, cancer and neurodegeneration, as well as rare diseases
Overview:<A HREF="https://www.research.manchester.ac.uk/portal/viki.allan.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer"> Viki Allan</A>
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Modelling wound healing and inflammation in Drosophila: <A HREF="https://www.research.manchester.ac.uk/portal/Tom.Millard.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Tom Millard</A>
Modelling kidney disease in zebrafish: <A HREF="https://www.research.manchester.ac.uk/portal/martin.p.lowe.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Martin Lowe</A>
Cell-matrix interactions in ovarian cancer: <A HREF="https://www.research.manchester.ac.uk/portal/patrick.caswell.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Pat Caswell</A>
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14:25 Individual discussions clinicians-scientists
 
14:45 <A HREF="https://www.bmh.manchester.ac.uk/research/domains/cellular-development-systems/gecs/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Molecular Mechanisms of Gene Regulation</A>
Changes in gene expression underlie development, disease and evolution. Research looks at the mechanisms that instruct these changes, and their impact on developmental disorders and diseases such as cancer, fibrosis and arthritis.
Overview:<A HREF="https://www.research.manchester.ac.uk/portal/andrew.d.sharrocks.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer"> Andrew Sharrocks</A> 
Transcription factor networks: <A HREF="https://www.research.manchester.ac.uk/portal/paul.shore.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Paul Shore</A> 
Single cell approaches to gene expression: <A HREF="https://www.research.manchester.ac.uk/portal/pawel.paszek.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Pawel Paszek</A> 
Gene expression in a complex tissue environment: <A HREF="https://www.research.manchester.ac.uk/portal/karen.piperhanley.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Karen Piper-Hanley</A> 
 
15:20  Individual discussions clinicians-scientists
 
15:40 <A HREF="https://www.wellcome-matrix.org/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Cell Matrix Biology</A>
Matrix is essential for multicellular life; surrounding and supporting cells. Research on the relationship between cells and matrix helps understand cancer, fibrosis, inflammation and repair, healthy ageing, chronic diseases and identifying targets for disease intervention.
Overview: <A HREF="https://www.research.manchester.ac.uk/portal/karl.kadler.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Karl Kadler</A> 
Chronomatrix: <A HREF="https://www.research.manchester.ac.uk/portal/qing-jun.meng.html" TARGET="_blank" TITLE="https://www.research.manchester.ac.uk/portal/qing-jun.meng.html" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Qing-Jun Meng </A>
 
16:10 Individual discussions clinicians-scientists
 
16:30 Close
CPD points from the Royal College of Physicians will be applied for.
Background 
Forging New Links is a series of meetings to help basic scientists, clinicians, nursing, midwifery and allied health professionals develop new research collaborations in Manchester.  The MAHSC Women and Children Domain and the University of Manchester Cellular and Developmental Systems domain are the organisers. 
At the first meeting in November 2017, clinicians presented to scientists on clinical problems that would benefit from a molecular perspective. At this second meeting, University of Manchester scientists will present to healthcare professionals.
Aims
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To give an overview of how Manchester’s basic research in cellular and developmental systems increases our understanding of the cellular and molecular basis of diseases
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To help clinicians, nursing, midwifery and allied health professionals understand the opportunities for new research collaborations in cellular and developmental systems
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Dalton Room

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Forging New Links: Cellular and Developmental Systems

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