HDR UK Driver Programmes Symposium

Health Data Research UK (HDR UK) is the national institute for health data with a mission to unite the UK’s health data to enable discoveries that improve people’s lives. It is a charity funded by UK Research and Innovation, the Department of Health and Social Care in England and equivalents in Northern Ireland, Wales and Scotland, and leading medical research charities.

Health Data Research UK (HDR UK)

The symposium will feature two keynote talks, a panel discussion a virtual poster session and submitted abstracts.

The Big Data for Complex Disease consortium are delighted to host this symposium to bring together researchers from across HDR UK’s Driver Programmes and wider Institute who are interested in using health data modelling to understand risk and disease trajectories, better informing prediction, prevention, and treatment across the population. The symposium be an exciting opportunity to hear from researchers working with novel methodologies and tackling challenges in working with health data across a variety of diseases, co-morbidities, and types of EHRs. The symposium will feature two keynote talks, a panel discussion on the challenges of creating prediction models that deliver benefit for patients, a virtual poster session and short talks selected from submitted abstracts. We encourage participants to present on a range of topics to discuss the challenges faced (and potential solutions) when applying modelling approaches to longitudinal EHRs, including:Data challenges<ul><li>Dealing with diverse data, e.g., from multiple centres, primary and secondary care settings, and different data modalities</li><li>Addressing biases in data – methods to account for data missingness, loss to follow-up</li><li>Defining disease phenotypes and potential causality using longitudinal EHRs, including symptom-level data</li></ul>Modelling approaches<ul><li>Modelling of disease progression trajectories to understand co-morbidities and risk predictors</li><li>Dynamic risk prediction models and causal risk prediction models</li><li>Machine learning models for temporally sequenced data and repeated measurements</li></ul>Implementation<ul><li>Developing model evaluation metrics</li><li>Patient and public involvement and engagement (PPIE) in longitudinal EHR studies</li><li>Deploying EHR longitudinal models in clinical practice</li></ul> <h3>Speakers:</h3>We are very pleased to have agreed two excellent keynote speakers who will cover both statistical and machine learning approaches to modelling longitudinal data.<a href="https://eng.ox.ac.uk/people/tingting-zhu/" title="https://eng.ox.ac.uk/people/tingting-zhu/" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Professor Tingting Zhu</a> is Associate Professor in AI for Digital Health in the Department of Engineering Science at Oxford. Her research interests lie in machine learning for healthcare applications, and she has developed probabilistic techniques for reasoning about time-series medical data. Her work involves the development of machine learning for understanding complex patient data, with an emphasis on Bayesian inference, deep learning, and applications involving the developing world.<a href="https://profiles.ucl.ac.uk/48171-george-ploubidis" title="https://profiles.ucl.ac.uk/48171-george-ploubidis" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Professor George Ploubidis</a> is Professor of Population Health and Statistics at the UCL Social Research Institute. He is s a multidisciplinary quantitative social scientist and a longitudinal surveys methodologist. His research interests relate to socioeconomic and demographic determinants of health over the life course and the mechanisms that underlie generational differences in health, well-being and mortality. His methodological work in longitudinal surveys focusses on applications for handling missing data, causal inference and measurement error. <h3>Call for Abstracts</h3>We invite all members of the HDR UK Driver Programmes and wider health data research community to submit an abstract to the symposium. Please submit your abstract using this <a href="https://forms.office.com/e/f2Q2AyLMGa" title="https://forms.office.com/e/f2Q2AyLMGa" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Microsoft Form</a>.Deadline: Wednesday, 5 February 2025Abstract &amp; Short Talk selection confirmation: Friday, 21 February 2025Registration: You can submit your abstract without being registered. The presenting author must be registered at the time of the symposium to present their work.Abstract limit: There are no restrictions on the number of submissions you may submit.Language: Abstracts must be written and presented in Plain English. Please ensure that your abstract is written for a lay audience. For tips on writing for lay audience see: <a href="https://www.nihr.ac.uk/plain-english-summaries" title="https://www.nihr.ac.uk/plain-english-summaries" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Plain English summaries | NIHR</a> and <a href="https://www.youtube.com/watch?v=pOoJUDCP9J0" title="https://www.youtube.com/watch?v=pOoJUDCP9J0" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">BHF Data Science Centre Webinar "How Plain is your English?"</a>Character limit: There is a limit of 2500 characters for the text of your submission.Abstract submission criteria:<ul><li>Relevance to longitudinal health data modelling</li><li>Relevance to health data research</li><li>Originality and innovation of science</li><li>Feasibility of science</li><li>Quality and well-designed science</li></ul>Short Talk selection: Please indicate on the form whether you’d like your abstract to be considered for a short talk. Symposium organisers will choose 6 Short Talks from the submitted abstracts and all approved abstracts will be offered a virtual poster position automatically. Short talks will be selected based on topics that would be of high interest to the symposium audience, and the relevance to themes described above. <h3>Patient and Public Involvement and Engagement</h3>Patients and the public who kindly provide their health data are a fundamental to our research and we are delighted that they are part the symposium programme. We will have public contributors read and review the submitted abstracts as part of the panel for short talk selection. We are pleased to invite a public contributor to serve as a member of our panel discussion on the potential benefit disease prediction models can have on patients and members of the public.We are happy to welcome any lay representatives who would like to attend the symposium online. Please contact Amy Hodgkinson (<a href="mailto:amy.hodgkinson@hdruk.ac.uk" title="mailto:amy.hodgkinson@hdruk.ac.uk" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">amy.hodgkinson@hdruk.ac.uk</a>) to ensure any accessibility requirements and support are in place for attendance. If you have any queries or questions regarding this event please contact Alexis Webb at <a href="https://alexis.webb@hdruk.ac.uk" title="https://alexis.webb@hdruk.ac.uk" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">alexis.webb@hdruk.ac.uk</a>.

Agenda

Welcome

Keynote #1 

Longitudinal Analysis of Disease Trajectories of Multimorbidity through Process Mining Techniques - Areti Manataki, University of St Andrews; Longitudinal Study of Neighbourhood Characteristics and Mental Health in Childhood and Adolescence in England - Niloofar Shoari, Great Ormond Street Institute of Child Health; Characterising post-myocardial infarction disease trajectories using non-negative matrix factorisation: a nationwide analysis - Jonathan A. Batty, Leeds Institute for Data Analytics, University of Leeds; Use of national data collections to understand Lynch syndrome diagnostic testing pathways in endometrial cancers - Catherine Huntley, Institute of Cancer Research; Inequalities in asthma outcomes in England: a national cohort study - Zakariah Gassasse, Imperial College London; Mortality in adolescents with and without neurodisability in England: a national cohort study using linked health and education data from ECHILD - Louise Macaulay, University College London   

Short talks

Break - Virtual Poster Session

Keynote #2 

Panel discussion

Close

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HDR UK Driver Programmes Symposium

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