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Protein shakes – why the mobility of biomolecules matters

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Huxley Lecture Theatre

Huxley Building

Queensdown School Road

Brighton

BN2 4GJ

United Kingdom

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David Timson, Professor of Biochemistry and Head of the school of Pharmacy and Biomolecular Sciences at the University of Brighton, presents his inaugural lecture:

Protein shakes – why the mobility of biomolecules matters

Any undergraduate studying biochemistry will be taught that the structure of biological molecules determines their function. This is true. For example, enzymes (nature’s catalysts) have active sites which are adapted to complement the shape of the molecules they bind to. However, biological macromolecules like proteins are constantly in motion – shaking, wobbling and vibrating. This mobility is also critical to function, a point I will illustrate with examples from my own research on proteins. Mutations can result in changes to how proteins fold and move – events which can result in genetic diseases. My aim in this lecture is to demonstrate that protein structure and mobility determine biological function.

this lecture will take place between 6.30-7.30pm and is followed by a canape reception

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Huxley Lecture Theatre

Huxley Building

Queensdown School Road

Brighton

BN2 4GJ

United Kingdom

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