In vivo Tissue Reprogramming Seminar - Professor Chandan K Sen  Indiana

Research & Innovation Projects Team

Visiting Professor Chandan K Sen - Distinguished Professor, Indiana University School of Medicine - In vivo Tissue Reprogramming Seminar

Jean MacFarlane Building, Ground Floor 306b

Addressing the notion of functional tissue reprogramming in vivo. Such reprograming happens under immune surveillance and achieves desired functional gains at the system level without the need for any tissue grafting or cell transplantation. In our laboratories, such reprogramming is achieved by tissue nano-transfection technology or TNT. This tissue nano-transfection (TNT) approach allows direct cytosolic delivery of reprogramming factors by applying a highly intense and focused electric field through arrayed nanochannels, which benignly nanoporates the juxtaposing tissue cell membranes and electrophoretically drives reprogramming factors into the tissue. Emphasis will be placed on vasculogenic reprogramming of the skin with other examples including myogenic, neurogenic and neurotrophic outcomes. 

The speaker Professor Chandan K Sen (H-index 109) is a Distinguished Professor at the Indiana University School of Medicine and Professor at the Weldon School of Biomedical Engineering at Purdue. Dr. Sen directs the Indiana Center for Regenerative Medicine and Engineering.

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