Single Molecule Network meeting - 'Force Spectroscopy'

Single Molecule Network meeting - 'Force Spectroscopy'

We bring together scientists from London Institutes with a shared interest in single molecule approaches to biological research.

By The Francis Crick Institute

Date and time

Tuesday, May 7 · 1 - 5pm GMT+1

Location

Francis Crick Institute

1 Midland Road London NW1 1AT United Kingdom

Agenda

1:00 PM - 1:40 PM

Welcome and Lunch

1:40 PM - 1:45 PM

Introduction

1:45 PM - 2:05 PM

Studying DNA structure and repair with magnetic tweezers

Dr Nick Bell, University College London

2:05 PM - 2:25 PM

AFM - From single cell to tissue

Tong Zhu, King’s College London / The Francis Crick Inst

2:25 PM - 2:45 PM

Novel insights into Smc5/6 activity on single stranded DNA

Anno Koetje, Imperial College London

2:45 PM - 3:15 PM

Networking Coffee and Snacks

3:15 PM - 3:50 PM

Keynote talk - Adventures in Force Spectroscopy

Dr David Brockwell, University of Leeds

3:50 PM - 4:10 PM

The molecular dissipation of dsDNA and consequences for looping times predicti

Dr Bhavin Khatri, The Francis Crick Institute

About this event

  • 4 hours

Challenging questions in biomedical research require studying the individual: a single interaction, enzyme, or reactant. Measurements of such phenomena at high spatial and temporal resolutions reveal the intricacies and heterogeneities that occur. Studying the individual brings insight into the behaviour of the ensemble. The single-molecule methods required are inherently multi-disciplinary.


The purpose of this network is to break the isolation of traditional disciplines by focusing on the single-molecule, a perspective used across disciplines.


The aims of the network are to:

- Establish a network of cross-disciplinary researchers working with single-molecule methods

- Provide repeating forums for cross-discipline knowledge transfer between the Crick, partner universities, and others

Organized by

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the scientific mechanisms of living things. Its work is helping to understand why disease develops and to find new ways to treat, diagnose and prevent illness such as cancer, heart disease, stroke, infections and neurodegenerative diseases.

By bringing together scientists from many disciplines, the Crick will have the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease.

The Francis Crick Institute was founded by six of the UK's most successful scientific and academic organisations - the Medical Research CouncilCancer Research UKWellcome TrustUCLImperial College LondonKing's College London