Small, lightweight trace explosives detector Launch Webinar

UK Defence Innovation

This Defence and Security Accelerator (DASA) competition is seeking proposals for the development of novel, low burden, bioassay platforms

This webinar is now closed for registrations. Please contact the DASA Help Desk on Accelerator@dstl.gov.uk

This Defence and Security Accelerator (DASA) competition is seeking proposals for the development of novel, lightweight, bioassay systems for the detection of trace explosives. Systems to be considered for this competition will encompass novel transduction platforms, consumables and swab-based sample inputs for the trace detection of three specified explosives targets. Systems should have the potential to be developed in the future to detect additional (ideally up to 10) substances of relevance to Defence and Security, e.g. additional explosives and other small molecule targets.Key Information Delivery from the competition will be a small, lightweight system, encompassing a novel transduction platform, consumables and swab-based sample input as part of the system at a minimum technological reddiness level<a href="" title="" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer"> </a>of 4 (TRL 4), target of TRL 6, which could be rapidly exploited (i.e. reach TRL 9 within two years of project completion). The platform must be capable of multiplex detection of at least three specified targets initially, although the platform should be expandable to detect a wider range of targets (ideally up to 10) in one test in the future.For successful, funded proposals, three antibodies and corresponding hapten-protein conjugates based on the target materials, will be made available under contract (as GFE), subject to necessary approvals and on a case-by-case basis. Details of the binding profiles using a competitive ELISA format will be provided to all successful suppliers in receipt of GFE to inform experimental design. Proposals for platforms that use other suitably specific biological recognition elements and / or other biologically driven recognition approaches will also be accepted and the GFE antibodies can also be made available under contract to these suppliers, if successful (subject to necessary approval and on a case by case basis, as a benchmark. If the use of alternate biological elements is proposed the use of the supplied antibody reagents is highly desirable as a cross-platform performance benchmark, if applicable to the transduction methodology. Explosives solution standards will not be provided, but details of suitable suppliers will be made available to successful bidders. It is required that two prototypes of the platform will be delivered, along with details of the testing methodology and sufficient information, including training materials, and consumables to perform a total of 200 tests. These prototypes will be used by the UK and US after project completion to verify the platform’s performance (detection performance and mobile usability). If any part of the system is reusable, this must be clearly detailed and fewer items may be submitted as deliverables, provided this is clearly justified in the proposal and sufficient consumables are provided for the UK and US to perform a total of 200 tests. MOD and / or DOD may wish to source additional consumables and / or platforms for further testing, and as such the final deliverable must include a scalable costing and detail the time required for the supply of future materials. This should not be considered a route to procurement or manufacture. Where do I submit my proposal? Via the<a href="https://www.gov.uk/government/collections/defence-and-security-accelerator-submit-your-research-proposal" title="https://www.gov.uk/government/collections/defence-and-security-accelerator-submit-your-research-proposal" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer"> DASA Online Submission </a>Service for which you will require an account. Only proposals submitted through the DASA Online Submission Service will be accepted. Total funding available The total possible funding available for this competition is £600,000 (exc. VAT). One to two proposals will be funded in this competition.This competition is jointly funded by the UK Ministry of Defence (MOD) and the US Department of Defense (DOD), the relationship will operate under and be governed by an extant memorandum of understanding (MOU) between both nations. Both the MOD and DOD will have access to proposals submitted under this competition in order to jointly assess which proposals to fund.For further guidance <a href="https://www.gov.uk/guidance/defence-and-security-accelerator-how-your-proposal-is-assessed" title="https://www.gov.uk/guidance/defence-and-security-accelerator-how-your-proposal-is-assessed" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Click here</a> for more information on our competition process and how your proposal is assessed. Queries should be sent to the DASA Help Centre – <a href="" title="" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">accelerator@dstl.gov.u</a>k

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