UCL: Synaptopathies Symposium

The Synaptopathies initiative is funded by a Strategic Award from the Wellcome Trust to a team of researchers at the UCL Institute of Neurology and King’s College London, led by Professor Dimitri M Kullmann. The grant was awarded in 2014 with a start date in April 2015.

UCL Institute of Neurology - Synaptopathies

<H2>                                 2017 Annual Synaptopathies Symposium</H2>
<H2>                                                              At </H2>
<H2>                                          33 Queen Square Lecture Theatre </H2>
<H2>                                                              On                                          </H2>
<H2>                                       Friday, September 22nd, 2017</H2>
 
<H3> </H3>
<H3>About the symposium</H3>
The symposium is funded by a Wellcome Trust Strategic Award entitled "Synaptopathies: genetics, biophysics and circuit mechanisms of paroxysmal neurological disorders". 
Epilepsy, migraine and related paroxysmal neurological disorders affect over 15% of the population, and account for an enormous burden to the individual and to society. Progress in managing these diseases is slow, with many patients failing to respond to available medication. Understanding the mechanisms will be an essential step not only towards improved diagnosis, but also towards the development of rational therapies.
*This event is open to principal investigators, postdoctoral researchers and PhD students. A limited number of places will be made available to MSc students.*
 
<H3>Programme</H3>
<HR>
8.25            Registration, coffee
9.00            Dimitri Kullmann (UCL): Introduction
9.05            (Chair: Peter Goadsby)
9.05            Karen Steel (KCL) Role of synaptic pathologies in hearing impairment 
9.40            Patricia Salinas (UCL): Understanding the mechanisms modulating synapse degeneration and      recovery: implications for Alzheimer’s disease
10.15          John Wood (UCL) New insights into pain mechanisms
10.50          Coffee 
11.10          (Chair: Sanjay Sisodiya)
11.10          Andrew Fry (Cardiff) NMDA receptor mutations in patients with malformations of cortical development
 11.45          Sameer Zuberi (Glasgow): Sodium channel genes and epilepsies - developmental expression and phenotypes
12.20          Seth Grant (Edinburgh) The synaptome: single synapse molecular maps of the whole brain
12.55          Lunch &amp; Posters
14.00          (Chair: Henry Houlden)
14.00          Alasdair Coles (Cambridge): Psychosis and the synapse
14.35          (Short talk) Viorica Chelban (UCL) Next Generation sequencing and gene discovery in spastic ataxias
14.50          (Short talk) Oscar Bello (UCL) Structural mechanisms of synaptic neurotransmission
15.05          (Short talk) Erica Tagliatti (UCL): Regulation of synaptic vesicle release by synaptotagmin calcium sensitive ring-like oligomers
15.20          (Short talk) Christine Dixon (UCL) How do mutations in hippocalcin cause dystonia?
15.35          (Short talk) Emer O’Connor (UCL): An introduction to Neurogenetics.co.uk
15.50          Tea 
16.10          (Chair: James Jepson)
16.10          Dmitri Rusakov (UCL): Astroglia and synapses: a cloudy relationship
16.45          Nicola Hamilton (UCL): Calcium permeable TRP channels facilitate myelin decompaction in ischaemia
17.20          Gero Miesenboeck (Oxford): Light sleep
17.55          Reception
<HR>
Supported by the Wellcome Trust through a Strategic Award on Synaptopathies
 <A HREF="http://www.ucl.ac.uk/ion/synaptopathies" TARGET="_blank" TITLE="Synaptopathies" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">www.ucl.ac.uk/ion/synaptopathies</A>
<HR>

UCL Institute of Neurology

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UCL: Synaptopathies Symposium

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